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Disease

Common Variable Immune Deficiency (CVID) (2)
HOIL1 deficiency (2)
HOIL1/RBCK1 deficiency, MyD88 deficiency, NEMO deficiency (1)
Hyper IgE Recurrent Infection Syndrome (1)
Immunodeficiencies (1)
IRAK-4 deficiency, MyD88 deficiency (1)
IRF-7 deficiency (1)
MECP1 deficiency, IRAK1 deficiency (1)
NEMO deficiency, IRAK-4 deficiency, MyD88 deficiency, STAT1 deficiency, UNC931 deficiency (1)
P14/LAMTOR deficiency (1)
SMARCAL1 deficiency (1)
STAT1 deficiency (1)
Stat3 deficiency (1)
TBK1 deficiency, TLR3 deficiency, STAT1 deficiency (1)
TLR3 deficiency (1)
TRIF deficiency (1)
UNC93B1 deficiency (2)

Sample Source

B cells (3)
Fibroblast (8)
iPS (1)
Kidney Biopsy (1)
Neutrophils (1)
PBMC (5)
Whole Blood (4)

Species

Homo sapiens (19)

Analyst

Platform

Affymetrix HG-U133A (1)
Affymetrix HG-U133_Plus_2 (3)
Affymetrix HuGene 1.0 ST v1 (1)
Illumina Human-6 v2 (1)
Illumina HumanHT-12 v3 (2)
Illumina HumanHT-12 v4 (11)
Illumina HumanWG-6 v3 (1)

Institution

GEO (20)
Sample Set Platform Species Disease Sample Source Sample Count  
Interferon Signature in the Blood in Inflammatory Common Variable Immune Deficiency [Test Set]. GSE51404 Homo sapiens Common Variable Immune De ... Whole Blood 53
Complete TLR3 deficiency. GSE30951 Homo sapiens TLR3 deficiency PBMC, Fibroblast 44
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. GSE13300 Homo sapiens UNC93B1 deficiency B cells 5
Interferon Signature in the Blood in Inflammatory Common Variable Immune Deficiency [Training Set]. GSE51405 Homo sapiens Common Variable Immune De ... Whole Blood 83
Transcriptional analysis of whole blood in patients with auto-inflammatory disorders. GSE40561 Homo sapiens STAT1 deficiency Whole Blood 51
Transcriptome analysis in primary fibroblasts from HOIL-1-deficient patients upon TNF-a or IL-1b stimulation. GSE40560 Homo sapiens HOIL1 deficiency Fibroblast 54
In vitro responses of fibroblasts from patients with TBK1 deficiency after TLR3 dependent and independent stimuli. GSE38652 Homo sapiens TBK1 deficiency, TLR3 def ... Fibroblast 58
Transcriptome analysis in peripheral blood mononuclear cells (PBMC) from HOIL-1-deficient patients upon TNF-a or IL-1b stimulation. GSE40838 Homo sapiens HOIL1 deficiency PBMC 45
Response of IRF7-deficient peripheral blood mononuclear cells to pH1N1 influenza virus infection. GSE66486 Homo sapiens IRF-7 deficiency PBMC 18
In vitro response of fibroblasts isolated from patients with RBCK1 deficiency. GSE31064 Homo sapiens HOIL1/RBCK1 deficiency, M ... Fibroblast 46
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. GSE40593 Homo sapiens UNC93B1 deficiency iPS 18
Genome-wide profiling of whole blood from patients with defects in Toll-like receptors (TLRs) and IL-1Rs (the TIR pathway) signaling. GSE25742 Homo sapiens IRAK-4 deficiency, MyD88 ... Whole Blood 365
In vitro response of fibroblasts isolated from patients with immunodeficiencies. GSE12124 Homo sapiens NEMO deficiency, IRAK-4 d ... Fibroblast 72
Screening for differentially expressed genes in patients with a novel immunodeficiency syndrome. GSE6322 Homo sapiens P14/LAMTOR deficiency B cells 4
Defective Mitophagy in XPA via PARP1 activation and NAD+/SIRT1-depletion: Implications for neurodegeneration (human). GSE55484 Homo sapiens Immunodeficiencies Fibroblast 16
In vitro responses of PBMC and fibroblasts from patients with TRIF deficiency after TRIF dependent and independent stimuli. GSE32390 Homo sapiens TRIF deficiency PBMC, Fibroblast 27
Identification of IL-21-induced STAT3 dependent genes in human B cells. GSE51587 Homo sapiens Stat3 deficiency B cells 14
Inherited human IRAK-1 deficiency selectively abolishes TLR signaling in fibroblasts. GSE92466 Homo sapiens MECP1 deficiency, IRAK1 d ... Fibroblast 64
Increased Wnt and Notch signaling: A clue to the renal disease in Schimke immuno-osseous dysplasia?. GSE81156 Homo sapiens SMARCAL1 deficiency Kidney Biopsy 5
Neutrophil and PBMC gene expression data from Job's Syndrome. GSE8507   Hyper IgE Recurrent Infec ... Neutrophils, PBMC 141
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