Dataset with samples from Individuals with:

A- defects in Intrinsic and Innate Immunity:

1)- Herpes simplex encephalitis (HSE): UNC93B1 deficiency, Phenotype OMIM number 610551

2)- TLR signaling pathway deficiency:

- MyD88 deficiency, Phenotype OMIM number 612260

- IRAK-4 deficiency, Phenotype OMIM number 607676

3)- Predisposition to severe viral infection: STAT1 deficiency, Phenotype OMIM number 613796

B- Autoinflammatory disorders:

1)- Defects effecting the inflammasome:

- Muckle-Wells syndrome (MWS), Phenotype OMIM number 191900

- Chronic infantile neurological cutaneous articular syndrome (CINCA), Phenotype OMIM number 607115

- Mevalonate kinase deficiency (MVK), Phenotype OMIM number 260920

PID classification: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659841/